MUC1 antibody (FITC)
Quick Overview for MUC1 antibody (FITC) (ABIN641537)
Target
See all MUC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse Anti-Human CD227 [+FITC]
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Specificity
- Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. MCA1742F recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. DS-MB-00521 recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin.
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Characteristics
- Adhesion Molecule/Cell Surface
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Immunogen
- Urinary MUC-1 mucin
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Isotype
- IgG3
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Application Notes
- Flow Cytometry, Immunofluorescence
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 0.1 mg/ml
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Buffer
- Phosphate buffered saline pH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C
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- MUC1 (Mucin 1 (MUC1))
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Alternative Name
- CD227
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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