Endothelin antibody
Quick Overview for Endothelin antibody (ABIN642615)
Target
See all Endothelin AntibodiesReactivity
Host
Conjugate
Application
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Specificity
- DS-MB-01212 reacts with the C terminal of endothelins 1, 2 and 3. This antibody does not react with the endothelin precursor molecule or big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction. ImmunohistologyFrozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.
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Characteristics
- Rat Anti-Human Endothelin
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Purification
- Purified
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Immunogen
- Synthetic peptide corresponding to the c-terminal region of human endothelin (C,H,L,D,I,I,W), conjugated to BSA.
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Isotype
- IgG2b
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/ml
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Buffer
- Phosphate buffered saline
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- Endothelin
Target
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