EBV LMP2A antibody
This anti-EBV LMP2A antibody is a Rat antibody detecting EBV LMP2A in IHC (p) and WB. Suitable for Epstein-Barr Virus (EBV).
Catalog No. ABIN644979
Quick Overview for EBV LMP2A antibody (ABIN644979)
Target
EBV LMP2A
(Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
Reactivity
Epstein-Barr Virus (EBV)
Host
Rat
Conjugate
This EBV LMP2A antibody is un-conjugated
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Specificity
- DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
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Characteristics
- Rat Anti-Epstein-Barr Virus LMP2A
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Purification
- Purified
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Immunogen
- Bacterial TrpE-LMP2A fusion protein
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Isotype
- IgG2a
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
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Alternative Name
- Epstein-Barr Virus LMP2A
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Target Type
- Viral Protein
Target
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