EBV LMP2A antibody
EBV LMP2A
Reactivity: Epstein-Barr Virus (EBV)
IHC (p), WB, IHC
Host: Rat
Monoclonal
15F9
unconjugated
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- Target See all EBV LMP2A products
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Reactivity
- Epstein-Barr Virus (EBV)
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Host
- Rat
- Clonality
- Monoclonal
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Conjugate
- This EBV LMP2A antibody is un-conjugated
- Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B.
- Purification
- Affinity purified
- Immunogen
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Bacterial TrpE-LMP2A fusion protein.
Type of Immunogen: Fusion protein - Clone
- 15F9
- Isotype
- IgG1
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- Application Notes
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Approved: IHC, IHC-P, WB (1:100 - 1:1000)
Usage: Immunohistology: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. - Comment
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Target Species of Antibody: Epstein-Barr Virus
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
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Short term: -20°C
Long term: -20°C.
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- Target
- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
- Alternative Name
- EBV LMP2A (EBV LMP2A Products)
- Synonyms
- - antibody, LMP2A antibody
- Target Type
- Viral Protein
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