CRISP3 antibody
Quick Overview for CRISP3 antibody (ABIN648781)
Target
See all CRISP3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- FACS,Cell-ELISA
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Purification
- Protein G
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Immunogen
- genetic immunisation with cDNA encoding human Crisp3
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Isotype
- IgG1
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Application Notes
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
Restrictions
- For Research Use only
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Concentration
- 2 mg/mL
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Buffer
- PBS, pH 7.2
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C
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Storage Comment
- short term: 2 °C - 8 °C, long term: -20 °C
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- CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))
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Alternative Name
- Crisp3
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Background
- Cysteine-rich secretory protein 3 (CRISP3) belongs to the cysteine-rich secretory protein family. CRISPs are characterized by a cysteine-rich domain at the COOH terminal that form 8 intramolecular disulfide bonds. Mammalian members of the CRISP family are expressed predominantly in the male reproductive tract and are implicated in the process of reproduction from spermiogenesis, posttesticular sperm maturation and capacitation to oocyte-sperm fusion. CRISP3 is epithelium-specific and found predominantly in salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. CRISP3 is up-regulated in malignant prostatic epithelium, therefore, it can be used as a potential prostate cancer biomarker.
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UniProt
- P54108
Target
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