OCT4 antibody (pSer236)
Quick Overview for OCT4 antibody (pSer236) (ABIN650860)
Target
See all OCT4 (POU5F1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- pSer236
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Predicted Reactivity
- B, M, Pig
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This OCT4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S236 of human OCT4.
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Isotype
- Ig Fraction
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Application Notes
- DB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Alternative Name
- OCT4
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Background
- OCT4 encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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Molecular Weight
- 38571
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Gene ID
- 5460
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NCBI Accession
- NP_002692
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UniProt
- Q01860
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Pathways
- Stem Cell Maintenance
Target
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