BBS10 antibody (C-Term)

Catalog No. ABIN651074

The Rabbit Polyclonal anti-BBS10 antibody has been validated for WB and FACS. It is suitable to detect BBS10 in samples from Human.

Quick Overview for BBS10 antibody (C-Term) (ABIN651074)

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB24715

Product Details anti-BBS10 Antibody

Binding Specificity: AA 515-544, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BBS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-544 amino acids from the C-terminal region of human BBS10.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for BBS10

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Alternative Name: BBS10

Background: BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.

Molecular Weight: 80838

Gene ID: 79738

NCBI Accession: NP_078961

UniProt: Q8TAM1