BTG1 antibody (AA 92-118)

Catalog No. ABIN2840179

This Rabbit Polyclonal antibody specifically detects BTG1 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.It has been mentioned in 1 publication

Quick Overview for BTG1 antibody (AA 92-118) (ABIN2840179)

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26174

Product Details anti-BTG1 Antibody

Binding Specificity: AA 92-118

Predicted Reactivity: B, C, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BTG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human BTG1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-BTG1 antibody (ABIN2840179)

Zhang, Yang, Cai, Zhao, Sun, Li, Feng, Feng, Ye, Niu, Zhang: "miR-511 promotes the proliferation of human hepatoma cells by targeting the 3'UTR of B cell translocation gene 1 (BTG1) mRNA." in: Acta pharmacologica Sinica, Vol. 38, Issue 8, pp. 1161-1170, (2018) (PubMed).

Target Details for BTG1

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Alternative Name: BTG1

Background: BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8,12)(q24,q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.

Molecular Weight: 19209

Gene ID: 694

NCBI Accession: NP_001722

UniProt: P62324

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development