CNOT6L antibody (C-Term)

Catalog No. ABIN651400

This Rabbit Polyclonal antibody specifically detects CNOT6L in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CNOT6L antibody (C-Term) (ABIN651400)

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT6L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26522

Product Details anti-CNOT6L Antibody

Binding Specificity: AA 414-442, C-Term

Predicted Reactivity: X, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CNO6L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human CNO6L.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CNOT6L

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Alternative Name: CNO6L

Background: CNO6L plays a role in the deadenylation of mRNAs in the cytoplasm. CNO6L has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. CNO6L may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. This protein involved in deadenylation-dependent degradation of CDKN1B mRNA.

Molecular Weight: 63001

Gene ID: 246175

NCBI Accession: NP_653172

UniProt: Q96LI5