TNIP3 antibody (N-Term)

Catalog No. ABIN651787

This Rabbit Polyclonal antibody specifically detects TNIP3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TNIP3 antibody (N-Term) (ABIN651787)

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB27057

Product Details anti-TNIP3 Antibody

Binding Specificity: AA 74-102, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Alternative Name: TNIP3

Background: TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Molecular Weight: 38943

Gene ID: 79931

NCBI Accession: NP_001122315, NP_001231693, NP_079149

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin