TNIP3 antibody (AA 40-120)

Catalog No. ABIN7231850

This Rabbit Polyclonal antibody specifically detects TNIP3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TNIP3 antibody (AA 40-120) (ABIN7231850)

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TNIP3 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-TNIP3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TNIP3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TNIP3 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Alternative Name: TNIP3

Background: TNFAIP3-interacting protein 3, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene proteinTNIP3 (TNFAIP3 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Immune response IL-23 signaling pathway. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Molecular Weight: 35kD

Gene ID: 79931

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin