ENOS antibody (N-Term)

Catalog No. ABIN652267

This Rabbit Polyclonal antibody specifically detects ENOS in IF, FACS and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for ENOS antibody (N-Term) (ABIN652267)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENOS antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18211

Product Details anti-ENOS Antibody

Binding Specificity: AA 48-75, N-Term

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NOS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human NOS3.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ENOS antibody (ABIN652267)

Dabrowska, Uram, Zielinski, Rode, Sikora: "Oxidative stress and inhibition of nitric oxide generation underlie methotrexate-induced senescence in human colon cancer cells." in: Mechanisms of ageing and development, Vol. 170, pp. 22-29, (2018) (PubMed).

Target Details for ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Alternative Name: NOS3

Background: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases.

Molecular Weight: 133275

Gene ID: 4846

NCBI Accession: NP_000594, NP_001153581, NP_001153582, NP_001153583

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling