CCL3 antibody (C-Term)

Catalog No. ABIN652466

The Rabbit Polyclonal anti-CCL3 antibody has been validated for WB and IHC (p). It is suitable to detect CCL3 in samples from Human and Mouse. There are 2+ publications available.

Quick Overview for CCL3 antibody (C-Term) (ABIN652466)

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21614

Product Details anti-CCL3 Antibody

Binding Specificity: AA 59-87, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the C-terminal region of human CCL3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CCL3 antibody (ABIN652466)

Bignon, Gaudin, Hémon, Tharinger, Mayol, Walzer, Loetscher, Peuchmaur, Berrebi, Balabanian: "CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 3, pp. 886-96, (2014) (PubMed).

Wang, Lin, Izumi, Jiang, Lai, Xu, Fang, Lu, Li, Xia, Chang: "Increased infiltrated macrophages in benign prostatic hyperplasia (BPH): role of stromal androgen receptor in macrophage-induced prostate stromal cell proliferation." in: The Journal of biological chemistry, Vol. 287, Issue 22, pp. 18376-85, (2012) (PubMed).

Target Details for CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Alternative Name: CCL3

Background: Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.

Molecular Weight: 10085

Gene ID: 6348

NCBI Accession: NP_002974

UniProt: P10147

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy