PHD1 antibody (AA 194-221)
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- Target See all PHD1 (EGLN2) Antibodies
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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Binding Specificity
- AA 194-221
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This EGLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-221 amino acids from the Central region of human EGLN2.
- Clone
- RB22708
- Isotype
- Ig Fraction
- Top Product
- Discover our top product EGLN2 Primary Antibody
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anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 283-407) antibody
EGLN2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 58-107) antibodyEGLN2 Reactivity: Human, Cow, Guinea Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 150-250) antibodyEGLN2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 1-407) antibodyEGLN2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (C-Term) antibodyEGLN2 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 281-315) antibodyEGLN2 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse, Pig, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 Reactivity: Human, Mouse, Rat, Dog WB Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (N-Term) antibodyEGLN2 Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (C-Term) antibodyEGLN2 Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
- Alternative Name
- EGLN2 (EGLN2 Products)
- Background
- EGLN2 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation.
- Molecular Weight
- 43650
- Gene ID
- 112398
- NCBI Accession
- NP_444274, NP_542770
- UniProt
- Q96KS0
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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