DRD4 antibody (AA 365-391)

Catalog No. ABIN652706

The Rabbit Polyclonal anti-DRD4 antibody has been validated for WB, IHC (p) and FACS. It is suitable to detect DRD4 in samples from Human and Mouse. There is 1 publication available.

Quick Overview for DRD4 antibody (AA 365-391) (ABIN652706)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22909

Product Details anti-DRD4 Antibody

Binding Specificity: AA 365-391

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DRD4 antibody (ABIN652706)

Ma, Thapa, Morris, Michalakis, Biel, Frank, Bebak, Ding: "Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study." in: Human molecular genetics, Vol. 22, Issue 19, pp. 3906-19, (2013) (PubMed).

Target Details for DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Alternative Name: DRD4

Background: DRD4 is the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease.

Molecular Weight: 43901

Gene ID: 1815

NCBI Accession: NP_000788

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity