CYP8B1 antibody (C-Term)

Catalog No. ABIN652734

The Rabbit Polyclonal anti-CYP8B1 antibody (Clone RB17098) (ABIN652734) specifically detects CYP8B1 in WB, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for CYP8B1 antibody (C-Term) (ABIN652734)

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP8B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB17098

Product Details anti-CYP8B1 Antibody

Binding Specificity: AA 471-501, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CYP8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-501 amino acids from the C-terminal region of human CYP8B1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CYP8B1

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Alternative Name: CYP8B1

Background: CYP8B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless.

Molecular Weight: 58068

Gene ID: 1582

NCBI Accession: NP_004382

UniProt: Q9UNU6