CYP8B1 antibody (AA 303-440) (Biotin)

Catalog No. ABIN7142851

The Biotin-conjugated Rabbit Polyclonal anti-CYP8B1 antibody (ABIN7142851) specifically detects CYP8B1 in ELISA. The antibody is reactive with Human samples.

Quick Overview for CYP8B1 antibody (AA 303-440) (Biotin) (ABIN7142851)

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP8B1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CYP8B1 Antibody (Biotin)

Binding Specificity: AA 303-440

Purpose: CYP8B1 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase protein (303-440AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYP8B1

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Alternative Name: CYP8B1

Background:

Background: Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.

Aliases: 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase antibody, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase antibody, CP8B antibody, CP8B1_HUMAN antibody, CYP12 antibody, CYP8B1 antibody, CYPVIIIB1 antibody, Cytochrome P450 8B1 antibody, Cytochrome P450 subfamily VIIIB (sterol 12 alpha hydroxylase) polypeptide 1 antibody, Cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, Sterol 12-alpha-hydroxylase antibody

UniProt: Q9UNU6