PLCL1 antibody (N-Term)

Catalog No. ABIN2842522

The Rabbit Polyclonal anti-PLCL1 antibody is suitable to detect PLCL1 in samples from Human. It has been validated for WB and FACS.

Quick Overview for PLCL1 antibody (N-Term) (ABIN2842522)

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCL1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB22061

Product Details anti-PLCL1 Antibody

Binding Specificity: AA 149-176, N-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PLCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-176 amino acids from the N-terminal region of human PLCL1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PLCL1

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Alternative Name: PLCL1

Background: PLCL1 is an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a nhibitor of PPP1C.

Molecular Weight: 122728

Gene ID: 5334

NCBI Accession: NP_006217

UniProt: Q15111