Neuropilin 1 antibody (C-Term)

Catalog No. ABIN2842638

Cited in 1 publication. The Rabbit Polyclonal anti-Neuropilin 1 antibody (Clone RB22995) (ABIN2842638) specifically detects Neuropilin 1 in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Neuropilin 1 antibody (C-Term) (ABIN2842638)

Target: Neuropilin 1 (NRP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB22995

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: AA 722-750, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-750 amino acids from the C-terminal region of human NRP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Neuropilin 1 antibody (ABIN2842638)

Yoshizuka, Chen, Xu, Liao, Hong, Hu, Yu, Han, Chen, Sun: "A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis." in: Molecular and cellular biology, Vol. 32, Issue 3, pp. 606-18, (2012) (PubMed).

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF, MIM 192240) and semaphorin (see SEMA3A, MIM 603961) family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

Molecular Weight: 103134

Gene ID: 8829

NCBI Accession: NP_001019799, NP_003864

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals