Acrosin antibody (C-Term)

Catalog No. ABIN653021

The Rabbit Polyclonal anti-Acrosin antibody has been validated for WB and IHC (p). It is suitable to detect Acrosin in samples from Human.

Quick Overview for Acrosin antibody (C-Term) (ABIN653021)

Target: Acrosin (ACR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acrosin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB16798

Product Details anti-Acrosin Antibody

Binding Specificity: AA 387-416, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human ACR.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Acrosin

Target: Acrosin (ACR)

Alternative Name: ACR

Background: ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Molecular Weight: 45847

Gene ID: 49

NCBI Accession: NP_001088

UniProt: P10323

Pathways: cAMP Metabolic Process