Acrosin antibody (AA 201-300)

Catalog No. ABIN1387665

Cited in 4+ publications. The Rabbit Polyclonal anti-Acrosin antibody (ABIN1387665) specifically detects Acrosin in WB, FACS, IF (cc), IF (p), IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Acrosin antibody (AA 201-300) (ABIN1387665)

Target: Acrosin (ACR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acrosin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Acrosin Antibody

Binding Specificity: AA 201-300

Purpose: Acrosin Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acrosin

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Acrosin antibody (ABIN1387665)

Deng, Zhang, Yu, Wang, Chen, Han, Cheng, Lian, Liu et al.: "Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell ..." in: Oncotarget, Vol. 8, Issue 66, pp. 110592-110605, (2017) (PubMed).

Deng, Chen, Wang, Zhang, Tang, Li, Wang, Cheng, Jin, Li, Zhang, Yu, Lian, Liu, Liu: "Melatonin promotes development of haploid germ cells from early developing spermatogenic cells of Suffolk sheep under in vitro condition." in: Journal of pineal research, Vol. 60, Issue 4, pp. 435-47, (2016) (PubMed).

Liang, Cheng, Jiang, He, Wang, Jiang, Hou, Li, Liu, Wang: "The noncircadian function of the circadian Clock gene in the regulation of male fertility." in: Journal of biological rhythms, Vol. 28, Issue 3, pp. 208-17, (2013) (PubMed).

Target Details for Acrosin

Target: Acrosin (ACR)

Alternative Name: Acrosin

Background:

Synonyms: Acrosin, ACR, ACRS

Background: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.

Gene ID: 49

UniProt: P10323

Pathways: cAMP Metabolic Process