CDC14B antibody (AA 188-215)

Catalog No. ABIN653024

The Rabbit Polyclonal anti-CDC14B antibody is suitable to detect CDC14B in samples from Human. It has been validated for WB and FACS.

Quick Overview for CDC14B antibody (AA 188-215) (ABIN653024)

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC14B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB16909

Product Details anti-CDC14B Antibody

Binding Specificity: AA 188-215

Predicted Reactivity: M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CDC14B

Target: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Alternative Name: CDC14B

Background: CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Molecular Weight: 56802

Gene ID: 8555

NCBI Accession: NP_001070649, NP_003662, NP_201588

UniProt: O60729