SRC8 antibody (N-Term)

Catalog No. ABIN653194

This Rabbit Polyclonal antibody specifically detects SRC8 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SRC8 antibody (N-Term) (ABIN653194)

Target: SRC8 (SRC8 Protein (SRC8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24340

Product Details anti-SRC8 Antibody

Binding Specificity: AA 9-38, N-Term

Predicted Reactivity: C, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SRC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SRC8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SRC8

Target: SRC8 (SRC8 Protein (SRC8))

Alternative Name: SRC8

Background: SRC8 is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.

Molecular Weight: 61586

Gene ID: 2017

NCBI Accession: NP_001171669, NP_005222, NP_612632

UniProt: Q14247