Nyctalopin antibody (N-Term)

Catalog No. ABIN653436

The Rabbit Polyclonal anti-Nyctalopin antibody (Clone RB23621) (ABIN653436) specifically detects Nyctalopin in WB. The antibody is reactive with Human samples.

Quick Overview for Nyctalopin antibody (N-Term) (ABIN653436)

Target: Nyctalopin (NYX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nyctalopin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB23621

Product Details anti-Nyctalopin Antibody

Binding Specificity: AA 53-80, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NYX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NYX.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Nyctalopin

Target: Nyctalopin (NYX)

Alternative Name: NYX

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].

Molecular Weight: 52000

Gene ID: 60506

NCBI Accession: NP_072089

UniProt: Q9GZU5