Cytokeratin 1 antibody (AA 415-443)

Catalog No. ABIN653648

The Rabbit Polyclonal anti-Cytokeratin 1 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect Cytokeratin 1 in samples from Human. There is 1 publication available.

Quick Overview for Cytokeratin 1 antibody (AA 415-443) (ABIN653648)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18411

Product Details anti-Cytokeratin 1 Antibody

Binding Specificity: AA 415-443

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of human KRT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Cytokeratin 1 antibody (ABIN653648)

Liu, Zhong, Liu, Ye, Mao, Hu: "Differential miRNA expression profiles in human keratinocytes in response to protein kinase C inhibitor." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6608-6619, (2018) (PubMed).

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: KRT1

Background: KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

Molecular Weight: 66039

Gene ID: 3848

NCBI Accession: NP_006112

UniProt: P04264