IDH3G antibody (C-Term)

Catalog No. ABIN653754

The Rabbit Polyclonal anti-IDH3G antibody (Clone RB24877) (ABIN653754) specifically detects IDH3G in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for IDH3G antibody (C-Term) (ABIN653754)

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3G antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB24877

Product Details anti-IDH3G Antibody

Binding Specificity: AA 366-393, C-Term

Predicted Reactivity: B, Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IDH3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human IDH3G.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for IDH3G

Target: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Alternative Name: IDH3G

Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.

Molecular Weight: 42794

Gene ID: 3421

NCBI Accession: NP_004126, NP_777358

UniProt: P51553