This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-223 amino acids from the Central region of human CFP.
CFP
Reactivity: Human
WB
Host: Mouse
Polyclonal
unconjugated
Application Notes
WB: 1:500. FC: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target
CFP
(Complement Factor P (CFP))
Alternative Name
CFP
Background
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.