TAF2 antibody (C-Term)

Catalog No. ABIN653923

This Rabbit Polyclonal antibody specifically detects TAF2 in WB, FACS and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TAF2 antibody (C-Term) (ABIN653923)

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23821

Product Details anti-TAF2 Antibody

Binding Specificity: AA 1152-1180, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1180 amino acids from the C-terminal region of human TAF2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TAF2

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Alternative Name: TAF2

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.

Molecular Weight: 136971

Gene ID: 6873

NCBI Accession: NP_003175

UniProt: Q6P1X5