TAF2 antibody (C-Term)

Catalog No. ABIN955066

This Rabbit Polyclonal antibody specifically detects TAF2 in WB, FACS, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TAF2 antibody (C-Term) (ABIN955066)

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TAF2 Antibody

Binding Specificity: AA 1159-1188, C-Term

Specificity: This antibody reacts to TAF2.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1159~1188 amino acids from the C-terminal region of human TAF2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TAF2

Target: TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))

Alternative Name: TAF2

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.Synonyms: 150 kDa cofactor of initiator function, CIF150, RNA polymerase II TBP-associated factor subunit B, TAF2B, TAFII-150, TAFII150, TBP-associated factor 150 kDa, Transcription initiation factor TFIID subunit 2

Molecular Weight: 136971 Da

Gene ID: 6873

NCBI Accession: NP_003175