DPAGT1 antibody (AA 286-315)

Catalog No. ABIN653925

Cited in 1 publication. The Rabbit Polyclonal anti-DPAGT1 antibody (Clone RB23874) (ABIN653925) specifically detects DPAGT1 in WB. The antibody is reactive with Human samples.

Quick Overview for DPAGT1 antibody (AA 286-315) (ABIN653925)

Target: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPAGT1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB23874

Product Details anti-DPAGT1 Antibody

Binding Specificity: AA 286-315

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DPAGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human DPAGT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DPAGT1 antibody (ABIN653925)

Klein, Robb, Rushing, Liu, Belaya, Beeson: "Congenital myasthenic syndrome caused by mutations in DPAGT." in: Neuromuscular disorders : NMD, Vol. 25, Issue 3, pp. 253-6, (2015) (PubMed).

Target Details for DPAGT1

Target: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Alternative Name: DPAGT1

Background: DPAGT1 encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme.

Molecular Weight: 46090

Gene ID: 1798

NCBI Accession: NP_001373

UniProt: Q9H3H5