MUTED antibody (AA 40-68)

Catalog No. ABIN2843982

The Rabbit Polyclonal anti-MUTED antibody is suitable to detect MUTED in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for MUTED antibody (AA 40-68) (ABIN2843982)

Target: MUTED (Muted Homolog (MUTED))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUTED antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB22107

Product Details anti-MUTED Antibody

Binding Specificity: AA 40-68

Predicted Reactivity: Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MUTED

Target: MUTED (Muted Homolog (MUTED))

Alternative Name: MUTED

Background: This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.

Molecular Weight: 21609

Gene ID: 63915

NCBI Accession: NP_001186251, NP_958437

UniProt: Q8TDH9