Angiopoietin 1 antibody (C-Term)

Catalog No. ABIN654409

This Rabbit Polyclonal antibody specifically detects Angiopoietin 1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Angiopoietin 1 antibody (C-Term) (ABIN654409)

Target: Angiopoietin 1 (ANGPT1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB17673

Product Details anti-Angiopoietin 1 Antibody

Binding Specificity: AA 374-402, C-Term

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Alternative Name: ANGPT1

Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

Molecular Weight: 57513

Gene ID: 284

NCBI Accession: NP_001137, NP_001186788

UniProt: Q15389

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process