Actin-Like 7A antibody (N-Term)

Catalog No. ABIN654426

The Rabbit Polyclonal anti-Actin-Like 7A antibody (Clone RB22393) (ABIN654426) specifically detects Actin-Like 7A in WB. The antibody is reactive with Human samples.

Quick Overview for Actin-Like 7A antibody (N-Term) (ABIN654426)

Target: Actin-Like 7A (ACTL7A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin-Like 7A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB22393

Product Details anti-Actin-Like 7A Antibody

Binding Specificity: AA 41-67, N-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Actin-Like 7A

Target: Actin-Like 7A (ACTL7A)

Alternative Name: ACTL7A

Background: ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.

Molecular Weight: 48644

Gene ID: 10881

NCBI Accession: NP_006678

UniProt: Q9Y615