Complement Factor H antibody (AA 751-780)

Catalog No. ABIN654896

The Rabbit Polyclonal anti-Complement Factor H antibody is suitable to detect Complement Factor H in samples from Human. It has been validated for WB, IF and IHC (p).

Quick Overview for Complement Factor H antibody (AA 751-780) (ABIN654896)

Target: Complement Factor H (CFH)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor H antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18698

Product Details anti-Complement Factor H Antibody

Binding Specificity: AA 751-780

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids of human CFH.

Isotype: IgG

Application Details

Application Notes: IF: 1:25. IF: 1:25. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: CFH

Background: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 139096

Gene ID: 3075

NCBI Accession: NP_000177

UniProt: P08603

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin