UPP2 antibody (C-Term)

Catalog No. ABIN654948

The Rabbit Polyclonal anti-UPP2 antibody (Clone RB25318) (ABIN654948) specifically detects UPP2 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for UPP2 antibody (C-Term) (ABIN654948)

Target: UPP2 (Uridine Phosphorylase 2 (UPP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25318

Product Details anti-UPP2 Antibody

Binding Specificity: AA 217-244, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for UPP2

Target: UPP2 (Uridine Phosphorylase 2 (UPP2))

Alternative Name: UPP2

Background: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

Molecular Weight: 35527

Gene ID: 151531

NCBI Accession: NP_001128570, NP_775491

UniProt: O95045

Pathways: Ribonucleoside Biosynthetic Process