CNOT8 antibody (N-Term)

Catalog No. ABIN655064

Product Details anti-CNOT8 Antibody

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Binding Specificity: AA 34-61, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, C, Zf, M, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CAF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human CAF-1.

Clone: RB18739

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CNOT8

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Alternative Name: CAF-1 (CNOT8 Products)

Background: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Molecular Weight: 32745

Gene ID: 29883

NCBI Accession: NP_037486, NP_473367

UniProt: Q9UIV1