KSR2 antibody (C-Term)

Catalog No. ABIN655390

This Rabbit Polyclonal antibody specifically detects KSR2 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for KSR2 antibody (C-Term) (ABIN655390)

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KSR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB09886

Product Details anti-KSR2 Antibody

Binding Specificity: AA 603-638, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-638 amino acids from the C-terminal region of human KSR2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KSR2

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Alternative Name: KSR2

Background: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Molecular Weight: 107632

Gene ID: 283455

NCBI Accession: NP_775869

UniProt: Q6VAB6