HOPX antibody (C-Term)

Catalog No. ABIN655402

This Rabbit Polyclonal antibody specifically detects HOPX in WB and FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for HOPX antibody (C-Term) (ABIN655402)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB18900

Product Details anti-HOPX Antibody

Binding Specificity: AA 39-67, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HOPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the C-terminal region of human HOPX.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-HOPX antibody (ABIN655402)

Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: "Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis." in: Molecular cancer research : MCR, Vol. 11, Issue 10, pp. 1235-47, (2013) (PubMed).

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX

Background: The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq].

Gene ID: 84525

NCBI Accession: NP_001138931, NP_001138932, NP_115884, NP_631957, NP_631958

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation