UGT8 antibody (AA 366-393)

Catalog No. ABIN655577

Product Details anti-UGT8 Antibody

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Binding Specificity: AA 366-393

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.

Clone: RB29672

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-UGT8 antibody (ABIN655577)

Qi, He, Jia, Song, Guo, Ma, Wang, Xu, Fu, Li, Luo: "The miR-30 Family Inhibits Pulmonary Vascular Hyperpermeability in the Premetastatic Phase by Direct Targeting of Skp2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 13, pp. 3071-80, (2015) (PubMed).

Target Details for UGT8

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Alternative Name: UGT8 (UGT8 Products)

Background: Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].

Molecular Weight: 61438

Gene ID: 7368

NCBI Accession: NP_001121646, NP_003351

UniProt: Q16880

Pathways: Cell-Cell Junction Organization