TOR2A antibody (AA 194-221)

Catalog No. ABIN656112

The Rabbit Polyclonal anti-TOR2A antibody (Clone RB32220) (ABIN656112) specifically detects TOR2A in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TOR2A antibody (AA 194-221) (ABIN656112)

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32220

Product Details anti-TOR2A Antibody

Binding Specificity: AA 194-221

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-221 amino acids from the Central region of human TOR2A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TOR2A

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Alternative Name: TOR2A

Background: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

Molecular Weight: 35714

Gene ID: 27433

NCBI Accession: NP_001078816, NP_001127902, NP_001127903, NP_001238947, NP_001238950, NP_001238952, NP_569726

UniProt: Q5JU69