LILRB4 antibody (N-Term)

Catalog No. ABIN656231

The Rabbit Polyclonal anti-LILRB4 antibody is suitable to detect LILRB4 in samples from Human. It has been validated for WB.

Quick Overview for LILRB4 antibody (N-Term) (ABIN656231)

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB31065

Product Details anti-LILRB4 Antibody

Binding Specificity: AA 44-73, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LILRB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human LILRB4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LILRB4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for LILRB4

Target: LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))

Alternative Name: LILRB4

Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 49356

Gene ID: 11006

NCBI Accession: NP_001265355, NP_001265356, NP_001265358, NP_001265359

UniProt: Q8NHJ6