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FYB antibody (C-Term)

This anti-FYB antibody is a Rabbit Polyclonal antibody detecting FYB in WB. Suitable for Human.
Catalog No. ABIN656241

Quick Overview for FYB antibody (C-Term) (ABIN656241)

Target

See all FYB Antibodies
FYB (FYN-Binding Protein (FYB))

Reactivity

  • 44
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
Human

Host

  • 37
  • 6
  • 1
Rabbit

Clonality

  • 38
  • 6
Polyclonal

Conjugate

  • 25
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FYB antibody is un-conjugated

Application

  • 28
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  • 7
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  • 3
  • 3
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  • 1
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  • 1
Western Blotting (WB)

Clone

RB31088
  • Binding Specificity

    • 15
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 646-675, C-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This FYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-675 amino acids from the C-terminal region of human FYB.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    FYB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Expiry Date

    6 months
  • Target

    FYB (FYN-Binding Protein (FYB))

    Alternative Name

    FYB

    Background

    FYB acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.

    Molecular Weight

    85387

    Gene ID

    2533

    NCBI Accession

    NP_001230022, NP_001456, NP_955367

    UniProt

    O15117

    Pathways

    TCR Signaling, Protein targeting to Nucleus
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