PCDHB14 antibody (N-Term)

Catalog No. ABIN656255

The Rabbit Polyclonal anti-PCDHB14 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect PCDHB14 in samples from Human.

Quick Overview for PCDHB14 antibody (N-Term) (ABIN656255)

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB14 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31603

Product Details anti-PCDHB14 Antibody

Binding Specificity: AA 166-193, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHB14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the N-terminal region of human PCDHB14.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCDHB14 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Alternative Name: PCDHB14

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Molecular Weight: 87548

Gene ID: 56122

NCBI Accession: NP_061757

UniProt: Q9Y5E9