PCDHB14 antibody (Protocadherin beta 14) (AA 165-193)

Details for Product anti-PCDHB14 Antibody No. ABIN954043
Antigen
Epitope
AA 165-193, N-Term
10
9
7
2
1
1
1
Reactivity
Human
38
1
1
1
1
1
1
1
Host
Rabbit
35
3
Clonality
Polyclonal
Conjugate
This PCDHB14 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
17
17
17
13
5
Options
Immunogen Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 165-193aa) of human PCDHB14.
Isotype Ig Fraction
Specificity This antibody detects human PCDHB14 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a protein A column; followed by peptide affinity purification.
Antigen
Alternative Name PCDHB14 (PCDHB14 Antibody Abstract)
Background The PCDHB14 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-14, Protocadherin beta-14
Gene ID 56122
NCBI Accession NP_061757
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Protocadherin beta 14 (PCDHB14) (AA 165-193), (N-Term) antibody (ABIN954043) Immunohistochemistry analysis in human brain tissue (formalin-fixed, paraffin-embedde...
Image no. 2 for anti-Protocadherin beta 14 (PCDHB14) (AA 165-193), (N-Term) antibody (ABIN954043) Western blot analysis in K562 cell line lysates (35ug/lane) using PCDHB14  Antibody (...