PCCA antibody (AA 362-390)

Catalog No. ABIN656262

The Rabbit Polyclonal anti-PCCA antibody (Clone RB31944) (ABIN656262) specifically detects PCCA in WB and IHC (p). The antibody is reactive with Human and Rat samples.

Quick Overview for PCCA antibody (AA 362-390) (ABIN656262)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31944

Product Details anti-PCCA Antibody

Binding Specificity: AA 362-390

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-390 amino acids from the Central region of human PCCA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCCA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 80059

Gene ID: 5095

NCBI Accession: NP_000273, NP_001121164, NP_001171475

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process