SNRPD3 antibody (N-Term)

Catalog No. ABIN656384

There is 1 publication for this product available. The Rabbit Polyclonal anti-SNRPD3 antibody is suitable to detect SNRPD3 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for SNRPD3 antibody (N-Term) (ABIN656384)

Target: SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa (SNRPD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31276

Product Details anti-SNRPD3 Antibody

Binding Specificity: AA 9-38, N-Term

Predicted Reactivity: D, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SNRPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SNRPD3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:1000. IHC-P-Leica: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

References for anti-SNRPD3 antibody (ABIN656384)

Chan-Penebre, Kuplast, Majer, Boriack-Sjodin, Wigle, Johnston, Rioux, Munchhof, Jin, Jacques, West, Lingaraj, Stickland, Ribich, Raimondi, Scott, Waters, Pollock, Smith, Barbash, Pappalardi, Ho et al.: "A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. ..." in: Nature chemical biology, Vol. 11, Issue 6, pp. 432-7, (2015) (PubMed).

Target Details for SNRPD3

Target: SNRPD3 (Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa (SNRPD3))

Alternative Name: SNRPD3

Background: The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.

Molecular Weight: 13916

Gene ID: 6634

NCBI Accession: NP_001265585, NP_004166

UniProt: P62318

Pathways: Ribonucleoprotein Complex Subunit Organization