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PREX1 antibody (C-Term)
PREX1
Reactivity: Human
WB, FACS, IHC (p)
Host: Rabbit
Polyclonal
RB31307
unconjugated
Product Details anti-PREX1 Antibody
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Target
See all PREX1 Antibodies
PREX1
(Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))
Binding Specificity
All epitopes for PREX1 antibodies
AA 1134-1163, C-Term
Reactivity
All reactivities for PREX1 antibodies
Human
Host
All hosts for PREX1 antibodies
Rabbit
Clonality
All clonalities for PREX1 antibodies
Polyclonal
Conjugate
All conjugates for PREX1 antibodies
This PREX1 antibody is un-conjugated
Application
All applications for PREX1 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1.
Clone
RB31307
Isotype
Ig Fraction
Alternatives
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Application Details
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Application Notes
WB: 1:2000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:10~50. FC: 1:25
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
PREX1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Target Details for PREX1
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Target
PREX1
(Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))
Alternative Name
PREX1 (PREX1 Products )
Synonyms
MGC68772 antibody, P-REX1 antibody, G630042G04 antibody, Setd6 antibody, RGD1306534 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antibody, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antibody, prex1.L antibody, PREX1 antibody, prex1 antibody, Prex1 antibody
Background
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Gene ID
57580
NCBI Accession
NP_065871
UniProt
Q8TCU6
Pathways
Regulation of Actin Filament Polymerization
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