TMEM43 antibody (AA 195-223)

Catalog No. ABIN2845811

The Rabbit Polyclonal anti-TMEM43 antibody is suitable to detect TMEM43 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for TMEM43 antibody (AA 195-223) (ABIN2845811)

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM43 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32139

Product Details anti-TMEM43 Antibody

Binding Specificity: AA 195-223

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TMEM43 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Alternative Name: TMEM43

Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Molecular Weight: 44876

Gene ID: 79188

NCBI Accession: NP_077310

UniProt: Q9BTV4