PCDHA7 antibody (AA 272-300)

Catalog No. ABIN656584

This Rabbit Polyclonal antibody specifically detects PCDHA7 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PCDHA7 antibody (AA 272-300) (ABIN656584)

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB30194

Product Details anti-PCDHA7 Antibody

Binding Specificity: AA 272-300

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human PCDHA7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCDHA7 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for PCDHA7

Target: PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Alternative Name: PCDHA7

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molecular Weight: 100865

Gene ID: 56141

NCBI Accession: NP_061733, NP_114040

UniProt: Q9UN72