IREB2 antibody (AA 201-230)
Quick Overview for IREB2 antibody (AA 201-230) (ABIN656586)
Target
See all IREB2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 201-230
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Predicted Reactivity
- M, Pig, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2.
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Isotype
- Ig Fraction
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anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 39-281) antibody
IREB2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1F3 unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (Internal Region) antibodyVerified IREB2 Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 107-216) antibodyIREB2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-250) antibodyIREB2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 208-238), (Middle Region) antibodyIREB2 Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (Middle Region) antibodyIREB2 Reactivity: Human, Rat, Mouse, Pig, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) antibodyIREB2 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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Application Notes
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- IREB2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Expiry Date
- 6 months
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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Alternative Name
- IREB2
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Background
- IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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Molecular Weight
- 105059
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Gene ID
- 3658
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NCBI Accession
- NP_004127
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UniProt
- P48200
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Pathways
- Transition Metal Ion Homeostasis
Target
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